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Product name: Tibolone Synonyms: Livial,Liviella CAS No: 5630-53-5 EINECS:227-069-1 Molecular Formula: C26H34O4 Molecular Weight:312.45 Assay: 97.0%~103.0% Appearance: White or off-white crystalline powder Grade: Pharmaceutical Grade Usage: Can be used as pharmaceutical material, It is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women. Tibolone Livial/Liviella is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction. Tibolone is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women. It is a synthetic steroid that has the same activity as the female sex hormones estrogen and progesterone and the androgen testosterone. Tibolone helps restore hormonal balance in the body. When estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. In addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness. Tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. It restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.  

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