Price : $1.00 jack
28-11-17 0 Hits

Product Name:SR9011 CAS NO.:1379686-29-9 Molecular Formula:C23H31ClN4O3S Molecular Weight:479.03524 Purity:99% Appearance:White Powder Grade:Pharmaceutical Grade SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

>http://985671628.global-trade-center.com

288# Xinfeng Road,Jianggan District,Hangzhou,Zhejiang,China


Send Message Phone: 13385818498

Related ads

+91-9878377317 Business carrier success ,loss problem solution tantrik

+919878377317 VASHIKARAN SPECIALIST TANTRIK VISHAWNATH JI. Tantrik vishawnath is the most experienced and world reputed astrologer in India. अब घर बेठे पाए अपने जीवन की जटिल समस्या का समाधान Edhar udhar na bhatke kyunki aap ki samsya ka samadhan hamare…

Buy Fake Passports,Driver’s License,COUNTERFEIT,Whatsapp .+44 7537183414

Buy Fake Passports,Driver’s License,ID Cards,BUY SSD SOLUTION,COUNTERFEIT MONEY, Whatsapp.+44 7537183414 Hello, Getting a fake and a real (genuine) passport, ID or driving license or any other document is simple. we can make you both real and fake…

Triaminodil,R30490,Mephedrone,MDPV. jackgota@gmail.com

We sell quality products. get to us by email for details  email: jackgota@gmail.com

Buy Xanax, Rohypnol, Nembutal, Roxycodone, Opana, Adderall, Oxycontin, Vicodin, Percocet, etc..(30% Discount)

We supply good quality Benzodiazepines, Pain Medications, Anxiety Medications, Relief Medications, Insomnia Medications, Weight Lost Medications, Stimulants, Opiate/Opioid, Research Chemicals, HGH, etc... We now offer 30% Discount, Contact us or Check out…

China vendor BK bk-ebdp dibutylone BKEBDP methylone sophia@aosinachem.com,Skype: sophia_3317

E-mail:sophia@aosinachem.com   Skype:sophia_3317   HUBEI AOSINA CHEM-TECH CO.,LTD  www.aosinachem.com   We are one of the biggest leading manufacturers producing various research chemicals,our price and quality are pretty good.  Supply products as below:…

Report this ad